Anticancer agent 64 - CAS 2387902-92-1

Anticancer agent 64 (compound 5m) exhibits potent cytotoxicity against CCRF-CEM cells with an IC50 value of 2.4 μM, induces apoptosis by activating caspase 3 and 7 and causing PARP cleavage, and significantly disrupts mitochondrial membrane potential, thereby contributing to its anticancer efficacy [1].

Others, Apoptosis, Caspase, Bcl-2 Family, PARP

Others, Proteases/Proteasome, Apoptosis, Chromatin/Epigenetic, DNA Damage/DNA Repair

2387809

C31H46N2O2S

510.77

C(O)(=O)[C@]12[C@@]([C@@]3([C@@](C)(CC1)[C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)(C(C)(C)C6=C(C5)SC(N)=N6)[H])[H])[H])([C@H](C(C)=C)CC2)[H]

-20°C

Ice Packs

Small Compound