Anticancer agent 65 - CAS 2407861-48-5

Anticancer agent 65 showed good results in tumour cell lines, especially A549 cells (IC50: 1.07 μM) . anticancer agent 65 blocked the cell cycle of A549 cells in S phase, induced apoptosis, increased the expression of p53 and p21, and contributed to ROS generation and MMP collapse.

Others, MMP, MDM-2/p53, Bcl-2 Family, Apoptosis, Reactive Oxygen Species

Proteases/Proteasome, Immunology/Inflammation, Apoptosis, Metabolism, NF-κB, Others

2407808

C36H63NO5

589.89

C[C@]12[C@@]3(C)[C@@]([C@@]([C@](CCCC(C)(C)O)(C)O)(CC3)[H])([C@H](O)C[C@@]1([C@]4(C)[C@@](CC2)(C(C)(C)[C@@H](OC(=O)C5CCNCC5)CC4)[H])[H])[H]

-20°C

Ice Packs

Small Compound