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Antidepressant agent 8 - CAS 3066104-04-6

Antidepressant agent 8 - CAS 3066104-04-6

MF-0113645-01

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Product Details

  • Bioactivity

    Antidepressant agent 8 (Compound 1f) acts as a selective antagonist for the NMDA receptor GluN1/2A (NMDA receptorGluN1/2A), with an IC50 of 2.94 μmol/L. In a hydrocortisone-induced zebrafish depression model, it demonstrates antidepressant-like effects and shows good blood-brain barrier penetration.

  • Target

    IGluR

  • Related Pathways

    Neuroscience, Membrane transporter/Ion channel

  • CAS Number

    3066104-04-6

  • Molecular Formula

    C18H23FN4OS2

  • Molecular Weight

    394.53

  • SMILES

    O=C(NCC1CCCCC1)CSC2=NN=C(S2)NCC=3C=CC=C(F)C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound