Antidepressant agent 9 - CAS 143899-90-5

Antidepressant agent 9 (Compound 24) is an orally active inhibitor of NMDAR and SERT, with IC50 values of 3.50 μM and 1044 nM, respectively. It exhibits good metabolic stability and plasma exposure, and demonstrates antidepressant-like effects in the forced swim test in mice.

Serotonin Transporter, iGluR

Membrane transporter/Ion channel, Neuroscience

143804

C17H24N2

256.386

CN1[C@@]2([C@@]3([C@@](C=4C(C2)=CC=C(N)C4)(CC1)CCCC3)[H])[H]

-20°C

Ice Packs

Small Compound