Antifungal agent 122 - CAS 3054212-80-2

Antifungalagent 122 (compound 201), a potent and broad-spectrum antifungal agent, prevents the phase shift in fungi and the formation of fungal biofilms. This compound effectively inhibits the enzymatic activity of CYP3A4-M and CYP3A4-T, with IC50 values of 2.11 and 4.53 μM, respectively. Notably, Antifungalagent 122 exhibits no cytotoxicity.

Antifungal, Cytochromes P450

Metabolism, Microbiology/Virology

3054130

C28H24F4N4O

508.51

[C@](CN1C=NC=N1)([C@H](N(CC2=CC=C(C#CC3=C(F)C=C(F)C=C3)C=C2)C)C)(O)C4=C(F)C=C(F)C=C4

-20°C

Ice Packs

Small Compound