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Antiproliferative agent-72 - CAS 1052646-54-4

Antiproliferative agent-72 - CAS 1052646-54-4

MF-0119473-01

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Product Details

  • Bioactivity

    Antiproliferative agent-72 (Compound 10) is an Hsp90 inhibitor with a dissociation constant (Kd) of 11 nM. It exhibits antiproliferative activity with IC50 values of 1.5 μM and 1.1 μM against HCT116 and NCI-N87 cells, respectively. Antiproliferative agent-72 is suitable for cancer research applications.

  • Target

    HSP

  • Related Pathways

    Metabolism, Cytoskeletal Signaling

  • CAS Number

    1052588

  • Molecular Formula

    C20H17Cl2N3O2S

  • Molecular Weight

    434.34

  • SMILES

    ClC1=CC(Cl)=C2C=C1OCCCCOC3=CC=CC(SC4=NC(=NC2=C4)N)=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound