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Antitumor agent-138 - CAS 2975168-22-8

Antitumor agent-138 - CAS 2975168-22-8

MF-0147293-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    Antitumor agent-138 (compound 5b), with an IC 50 of 1.87 μM, inhibits tubulin polymerization at the tubulin colchicine-binding sites. It arrests the cell cycle at the G2/M phase and induces apoptosis in MCF-7 cells. Additionally, this compound suppresses cell migration and angiogenesis [1].

  • Target

    Apoptosis, Microtubule Associated

  • Related Pathways

    Apoptosis, Cytoskeletal Signaling

  • CAS Number

    2975168-22-8

  • Molecular Formula

    C20H21N3O4

  • Molecular Weight

    367.4

  • SMILES

    O=C(C1=CC(OC)=C(OC)C(OC)=C1)N2N=C(N)C=C2C=3C=CC(=CC3)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound