Antitumor agent-149 - CAS 2368983-54-2

Antitumor agent-149 (Compound 3), an analogue of Echinomycin, inhibits HIF-1α-mediated transcription, induces cancer cell apoptosis, and suppresses tumor growth in the SW620 xenograft mice model [1].

Apoptosis

Apoptosis

2368983-54-2

C52H64N10O14S

1085.19

C(N[C@@H]1COC(=O)[C@H](C(C)C)N(C)C(=O)[C@@]2(CSC[C@](N(C)C(=O)[C@H](C)NC1=O)(C(=O)N(C)[C@@H](C(C)C)C(=O)OC[C@@H](NC(=O)C3=NC4=C(C=C3O)C=CC=C4)C(=O)N[C@@H](C)C(=O)N2C)[H])[H])(=O)C5=NC6=C(C=C5O)C=CC=C6

-20°C

Ice Packs

Small Compound