Antitumor agent-37 - CAS 9007-83-4

Antitumor agent-37 exhibits potent anti-proliferative and anti-metastatic effects. antitumor agent-37 induces severe DNA damage, leading to high expression of γ-H2AX and p53. antitumor agent-37 induces apoptosis by exploiting the mitochondrial apoptosis pathway Bcl-2/Bax/caspase3. Antitumor agent-37 inhibits PD-L1 expression, increases CD3+ and CD8+ T-infiltrating cells in tumour tissue and significantly improves the immune response.

Others, Apoptosis

Apoptosis, Others

8920

C16H18Cl2N2O4Pt

568.32

-20°C

Ice Packs

Small Compound