Antitumor agent-60 - CAS 865784-65-2

Antitumor agent-60 is a potent antitumor agent that targets the RAS-RAF signaling pathway and binds to CRAF (Kd: 721.3 nM) . antitumor agent-60 increases p53 and ROS levels in cancer cells, resulting in oval and irregular nuclei. antitumor agent-60 is sufficient to block the cell cycle in G2/M phase and induce apoptosis. Antitumor agent-60 is sufficient to block the cell cycle in G2/M phase and induce apoptosis. In the A549 tumor transplantation model, Antitumor agent-60 has the ability to inhibit tumor growth.

Ras, Raf, MDM-2/p53, Apoptosis, ROS Kinase, Others

Others, Tyrosine Kinase/Adaptors, Apoptosis, MAPK, GPCR/G Protein

865717

C24H28O10S

508.54

C(=C/S(CC1=CC(OC(CCCC(O)=O)=O)=C(OC)C=C1)(=O)=O)\C2=C(OC)C=C(OC)C=C2OC

-20°C

Ice Packs

Small Compound