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Antitumor agent-67 - CAS 2820146-10-7
Antitumor agent-67 - CAS 2820146-10-7
SKU:MF-0160038-01
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Product Details
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Bioactivity
Antitumor agent-67 (compound 3), a potent antitumor agent, exhibits highly selective toxicity toward cancer cells while sparing normal cells. This compound can be activated by NQO1 to effectively release podophyllotoxin, thereby killing tumor cells. In HepG2 xenograft models, Antitumor agent-67 significantly inhibits cancer growth with minimal toxicity [1].
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Target
Microtubule Associated, Others
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Related Pathways
Cytoskeletal Signaling, Others
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CAS Number
2820146-10-7
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Molecular Formula
C45H47NO13
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Molecular Weight
809.85
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SMILES
O=C1[C@@]2([C@@H](C=3C([C@@H](OC(OCC4=CC=C(N(C(CC(C)(C)C5=C(C)C(=O)C(C)=C(C)C5=O)=O)C)C=C4)=O)[C@]2(CO1)[H])=CC6=C(C3)OCO6)C7=CC(OC)=C(OC)C(OC)=C7)[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound