Antiviral agent 25 - CAS 2761367-25-1

Antiviral agent 25 (compound 6g), a novel non-peptide analog covalent inhibitor of SARS-CoV-2 3CL pro, exhibits robust inhibitory activity against both SARS-CoV-2 3CL pro and SARS-CoV-2 PL pro, with IC50 values of 0.118 μM and 0.448 μM, respectively. Furthermore, it demonstrates significant antiviral effects against SARS-CoV-2, achieving an EC50 value of 7.249 μM [1].

Others, SARS-CoV

Microbiology/Virology, Others

2761341

C15H12FN3S

285.34

N(C)=C1N=C(N(S1)C2=CC=CC=C2)C3=CC=C(F)C=C3

-20°C

Ice Packs

Small Compound