Antiviral agent 35 - CAS 2760972-52-7

Antiviral agent 35 (compound 4d) is a potent oral inhibitor of the influenza virus, targeting early stages of viral replication. It suppresses influenza-induced ROS accumulation, autophagy, apoptosis, and the inflammatory response mediated by the RIG-1 pathway in a mouse model of pulmonary infection. Its cytotoxicity is minimal in MDCK cells, with a CC50 greater than 800 μM, and it has anti-H1N1 (A/Weiss/43) activity with an EC50 of 2.28 μM [1].

Influenza Virus

Microbiology/Virology

2760913

C23H18N2O4S

418.47

O=[N+](C(C=C1)=CC=C1S(N(C2=CC=CC3=C2C=CC=C3)CC4=CC=CC=C4)(=O)=O)[O-]

-20°C

Ice Packs

Small Compound