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Anxiolytic/nonsedative agent-1 - CAS 355022-97-8

Anxiolytic/nonsedative agent-1 - CAS 355022-97-8

SKU:MF-0046601-01

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  • Bioactivity

    Anxiolytic/nonsedative agent-1 (TCS 1205) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo.

  • Target

    GABA Receptor

  • Related Pathways

    Membrane transporter/Ion channel, Neuroscience

  • CAS Number

    354917

  • Purity

    0.9861

  • Molecular Formula

    C18H15N3O4

  • Molecular Weight

    337.33

  • SMILES

    C(C(N[C@H](C)C1=CC=CC=C1)=O)(=O)C=2C=3C(NC2)=CC=C(N(=O)=O)C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound