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Ap4dT - CAS 1146545-74-5
Ap4dT - CAS 1146545-74-5
SKU:MF-0112149-01
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Product Details
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Bioactivity
Ap4dT serves as an inhibitor of human adenylate kinase isozyme 1 (hAK1), effectively suppressing the synthesis of ATP and ADP, with IC50 values of 42 μM and 38 μM, respectively.
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Target
DNA/RNA Synthesis
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Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
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CAS Number
1146466
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Molecular Formula
C20H41N11O20P4
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Molecular Weight
879.5
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SMILES
O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP(OP(OC[C@H]2O[C@@H](N3C(NC(C(C)=C3)=O)=O)C[C@@H]2O)([O-])=O)([O-])=O)([O-])=O)([O-])=O)N4C5=NC=NC(N)=C5N=C4.[NH4+].[NH4+].[NH4+].[NH4+]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound