Apatinib-d8 - CAS 2468771-43-7

Apatinib-d8 is a deuterated compound of Apatinib. Apatinib has a CAS number of 811803-05-1. Apatinib is an orally bioavailable and specific VEGFR2 inhibitor (IC50: 1 nM) . In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.

Autophagy, c-RET, VEGFR, c-Kit, Src

Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors, Autophagy

2468771-43-7

C24H15D8N5O

405.52

C(#N)C1(C(C(C(C1([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])C2=CC=C(NC(=O)C3=C(NCC=4C=CN=CC4)N=CC=C3)C=C2

-20°C

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