APBC - CAS 324054-99-1

APBC is a novel PD-L1 inhibitor, effectively interrupting the PD-1/PD-L1 interaction by directly binding to PD-L1, presenting the KD and IC50 values at low-micromolar level, displaying superior antitumor efficacy in hPD-L1 knock-in B16F10-bearing mouse model without the induction of observable liver toxicity.

Others

Others

323954

C20H16N2O2

316.35

N(C(=O)C1=CC=C(C=C1)C2=CC=CC=C2)C3=C(C(N)=O)C=CC=C3

-20°C

Ice Packs

Small Compound