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Molfinity

Apcin - CAS 300815-04-7

Apcin - CAS 300815-04-7

MF-0017514-01

$39.90 USD
$39.90 USD
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Product Details

  • Bioactivity

    Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C (Cdc20) ) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. It acts by blocking mitotic exit and being synergistically amplified by co-addition of Ts-Arg-OMe.

  • Target

    APC/C

  • Related Pathways

    Cell Cycle/Checkpoint

  • CAS Number

    300815-04-7

  • Purity

    0.9674

  • Molecular Formula

    C13H14Cl3N7O4

  • Molecular Weight

    438.65

  • SMILES

    Cc1ncc(n1CCC(=O)NC(Nc1ccccc1)C(Cl)(Cl)Cl)[N+]([O-])=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound