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Molfinity

APE1-IN-2 - CAS 2923433-95-6

APE1-IN-2 - CAS 2923433-95-6

MF-0062971-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    APE1-IN-2 (compound AP1), a Pt (IV) proagent, selectively targets the essential base excision repair protein apurinic/apyrimidinic endonuclease 1 (APE1) . Exhibiting anticancer properties, APE1-IN-2 prompts the intracellular accumulation of platinum and initiates the activation of DNA damage response and apoptosis pathways [1].

  • Target

    MDM-2/p53, Apoptosis

  • Related Pathways

    Apoptosis

  • CAS Number

    2923332

  • Molecular Formula

    C9H12Cl2N4O5Pt

  • Molecular Weight

    522.21

  • SMILES

    O=[N+](C1=CC=CC2=C1NC(C(O[Pt]([NH3])(Cl)(O)(Cl)[NH3])=O)=C2)[O-]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound