Apelin-36 (rat, mouse) - CAS 230299-95-3

Endogenous APJ receptor agonist that is secreted by adipocytes. Binds with high affinity to APJ receptors (IC50 = 5.4 nM) and potently inhibits cAMP production in vitro (EC50 = 0.52 nM) . Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.

Apelin receptor, HIV Protease

Microbiology/Virology, Proteases/Proteasome, GPCR/G Protein

230201

C185H304N68O43S

4200.93

-20°C

Ice Packs

Peptide