APG-1387 - CAS 1570231-89-8

APG-1387 (SM-1387) is an IAP inhibitor that promotes the rapid degradation of cIAP1/2 and XIAP and exerts an anti-tumor effect on nasopharyngeal carcinoma stem cells. Studies have shown that APG-1387 combined with NPC's CDDP and 5-FU enhance chemoresensitivity and promote cell apoptosis in vitro and in vivo.

Others, Apoptosis, IAP

Others, Apoptosis

1570134

C60H72N10O10S2

1157.41

[H][C@]12CC[C@H](N1C(=O)[C@H](CN(CC2)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CC[C@@]2([H])CC[C@H](N2C(=O)[C@H](C1)NC(=O)[C@H](C)NC)C(=O)NC(c1ccccc1)c1ccccc1)NC(=O)[C@H](C)NC)C(=O)NC(c1ccccc1)c1ccccc1

-20°C

Ice Packs

Small Compound