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Molfinity

Aphidicolin 17-acetate - CAS 51103-57-2

Aphidicolin 17-acetate - CAS 51103-57-2

MF-0126029-01

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Product Details

  • Bioactivity

    Aphidicolin 17-acetate is a selective inhibitor of eukaryotic DNA polymerase α (DNA polymeraseα) that does not inhibit DNA polymerases β and γ. It significantly suppresses DNA synthesis in sea urchin embryos and HeLa cells in vivo without affecting RNA and protein synthesis.

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    Cell Cycle/Checkpoint, DNA Damage/DNA Repair

  • CAS Number

    51103-57-2

  • Molecular Formula

    C22H36O5

  • Molecular Weight

    380.518

  • SMILES

    O=C(OCC1(O)CCC23CC1CC3CCC4C(C)(CO)C(O)CCC42C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product