Apicidin - CAS 183506-66-3

Apicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiparasitic and antiproliferative activity. It attenuates memory deficits, inhibits cell growth and proliferation, and induces apoptosis and autophagy by decreasing Abeta load in APP/PS1 mice, making it a valuable tool for leukemia research.

Autophagy, Parasite, Apoptosis, HDAC

Autophagy, Apoptosis, Chromatin/Epigenetic, Microbiology/Virology, DNA Damage/DNA Repair

183437

0.9993

C34H49N5O6

623.78

[H][C@]12CCCCN1C(=O)[C@@]([H])(NC(=O)[C@H](Cc1cn(OC)c3ccccc13)NC(=O)[C@H](CCCCCC(=O)CC)NC2=O)[C@@H](C)CC

-20°C

Ice Packs

Natural Product