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Molfinity
Apicularen B - CAS 220757-06-2
Apicularen B - CAS 220757-06-2
SKU:MF-0125108-01
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Product Details
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Bioactivity
Apicularen B, a V-ATPase inhibitor and cytotoxic macrolide derived from the myxobacterium Archangium gephyra, can be utilized in studies of V-ATPase-related diseases such as osteopetrosis [1] [2].
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Target
Proton pump
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Related Pathways
Membrane transporter/Ion channel
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CAS Number
220757-06-2
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Molecular Formula
C33H44N2O11
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Molecular Weight
644.71
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SMILES
O=C1C=2C(C[C@]3(C[C@@H](O[C@H]4[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O4)C[C@@](O3)(C[C@H](C/C=C/NC(/C=C\C=C/CC)=O)O1)[H])[H])=CC=CC2O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product