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Apinocaltamide - CAS 1838651-58-3
Apinocaltamide - CAS 1838651-58-3
SKU:MF-0016457-01
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Product Details
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Bioactivity
Apinocaltamide (ACT-709478) is an orally available and selective T-type calcium channel blocker that penetrates the blood-brain barrier (BBB) with IC50=6.4-18nM for Cav3.1, Cav3.2, and Cav3.3, and is commonly used in epilepsy research.
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Target
Calcium Channel
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Related Pathways
Metabolism, Membrane transporter/Ion channel
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CAS Number
1838590
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Purity
0.998
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Molecular Formula
C22H18F3N5O
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Molecular Weight
425.41
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SMILES
N#CC1=CN=C(C=C1)CN2N=C(C=C2)NC(=O)CC3=CC=C(C=C3)C4(CC4)C(F)(F)F
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound