APJ receptor agonist 1 - CAS 2287153-38-0

APJ receptor agonist 1, a potent biphenyl acid derivative, acts as an agonist (EC50 of 0.093 nM and 0.12 nM for human and rat APJ receptors, respectively) for the APJ receptor (APJ-R) . It exhibits significant in vitro potency towards apelin-13, the endogenous peptidic ligand for the APJ receptor. APJ receptor agonist 1 holds promise for heart failure research.

Apelin receptor, Others

GPCR/G Protein, Others

2287115

C31H26ClN3O3

524.02

CCCC(NC(=O)c1ccc(c(c1)C(O)=O)-c1c(Cl)cccc1-c1nc2ccccc2[nH]1)c1ccccc1

-20°C

Ice Packs

Small Compound