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APKC-I - CAS 15854-12-3
APKC-I - CAS 15854-12-3
SKU:MF-0062990-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
APKC-I is an inhibitor of atypical protein kinase C (aPKC) which inhibits both PKCζ and PKCι with high specificity and prevents VEGF-induced endothelial permeability in cell culture and in vivo, thereby blocking ischemia-reperfusion (IR) -induced permeability.
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Target
Others, PKC
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Related Pathways
Others, Cytoskeletal Signaling, Chromatin/Epigenetic
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CAS Number
15839
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Molecular Formula
C15H17NO4S
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Molecular Weight
307.36
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SMILES
CCOC(=O)C1=C(N)SC=C1C1=CC(OC)=C(OC)C=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound