Aplaviroc hydrochloride - CAS 461023-63-2

Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc selectively inhibits the binding of a particular monoclonal antibody, 45531, to CCR5.

Others, HIV Protease, CCR

GPCR/G Protein, Immunology/Inflammation, Others, Microbiology/Virology, Proteases/Proteasome

460958

C33H44ClN3O6

614.17

Cl.CCCCN1C(=O)[C@H](NC(=O)C11CCN(Cc2ccc(Oc3ccc(cc3)C(O)=O)cc2)CC1)[C@H](O)C1CCCCC1

-20°C

Ice Packs

Small Compound