Aplidine - CAS 137219-37-5

Aplidine possesses antiviral activity against SARS-CoV-2 (IC90 = 0.88 nM) . Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2 (EEF1A2, Kd = 80 nM) .

DNA/RNA Synthesis, SARS-CoV

Microbiology/Virology, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

137177

0.9986

C57H87N7O15

1110.34

[H][C@@]12CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)C(=O)[C@@H](OC(=O)C[C@H](O)[C@]([H])(NC(=O)[C@@H](NC(=O)[C@@H](CC(C)C)N(C)C(=O)[C@@H]1CCCN1C(=O)C(C)=O)[C@@H](C)OC(=O)[C@H](Cc1ccc(OC)cc1)N(C)C2=O)[C@@H](C)CC)C(C)C

-20°C

Ice Packs

Small Compound