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Apomine - CAS 126411-13-0
Apomine - CAS 126411-13-0
SKU:MF-0015932-01
Regular price
$65.31 USD
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Sale price
$65.31 USD
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Product Details
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Bioactivity
Apomine (SR-9223i), an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and has been implicated in the regulation of myeloma in vivo. Apomine accelerates the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase and stimulates low-density lipoprotein receptor activity. Apomine enhances the antitumor effect of lovastatin on myeloma cells by downregulating 3-hydroxy-3-methylglutaryl-CoA reductase.
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Target
HMG-CoA Reductase, Apoptosis
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Related Pathways
Metabolism, Apoptosis
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CAS Number
126398
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Purity
>99.99%
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Molecular Formula
C28H52O7P2
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Molecular Weight
562.66
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SMILES
P(C(P(OC(C)C)(OC(C)C)=O)CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)(OC(C)C)(OC(C)C)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound