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Molfinity

Apomine - CAS 126411-13-0

Apomine - CAS 126411-13-0

SKU:MF-0015932-01

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  • Bioactivity

    Apomine (SR-9223i), an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and has been implicated in the regulation of myeloma in vivo. Apomine accelerates the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase and stimulates low-density lipoprotein receptor activity. Apomine enhances the antitumor effect of lovastatin on myeloma cells by downregulating 3-hydroxy-3-methylglutaryl-CoA reductase.

  • Target

    HMG-CoA Reductase, Apoptosis

  • Related Pathways

    Metabolism, Apoptosis

  • CAS Number

    126398

  • Purity

    >99.99%

  • Molecular Formula

    C28H52O7P2

  • Molecular Weight

    562.66

  • SMILES

    P(C(P(OC(C)C)(OC(C)C)=O)CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)(OC(C)C)(OC(C)C)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound