Apoptin-derived peptide - CAS 2232156-31-7

Apoptin-derived peptide, an antitumor polypeptide, exhibits cytotoxic effects by promoting apoptosis and necrosis in gastric cancer (GC) cells through the modulation of the PI3K / AKT / ARNT signaling pathway. It also impedes both the invasion and migration of cancer cells by inhibiting the expression and phosphorylation of the p85 subunit of PI3K, subsequently suppressing the PI3K / AKT pathway critical to gastric cancer development [1].

Akt, Apoptosis, PI3K

PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Apoptosis

2232156-31-7

C223H417N89O50S

5177.33

-20°C

Ice Packs

Peptide