Apoptosis inducer 24 - CAS 2763063-09-6

Apoptosisinducer 24 (Compound 4) inhibits the proliferation of gastric cancer cells with an IC50 range of 1.2-4.8 μM. It arrests the cell cycle at the G2/M phase, induces apoptosis in BGC-823 cells, and causes mitochondrial dysfunction. In mice, Apoptosisinducer 24 exhibits antitumor activity without significant toxicity, having an LD50 of 91.2 mg/kg.

Apoptosis

Apoptosis

2763063-09-6

C55H70BNO9

899.96

C(OCCCCOC(=O)C1=CC=C(OCC2=CC=C(C=C2)B3OC(C)(C)C(C)(C)O3)C=C1)(=O)[C@]45[C@]([C@@]6([C@@](C)(CC4)[C@@]7(C)C(=CC6=O)[C@]8(C)[C@@](CC7)(C(C)(C)C(=O)C(C#N)=C8)[H])[H])(CC(C)(C)CC5)[H]

-20°C

Ice Packs

Small Compound