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APPA - CAS 100750-39-8
APPA - CAS 100750-39-8
SKU:MF-0063035-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition of the polyol pathway. This compound shows promise for research into diabetic nephropathy (DN) [1].
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Target
Reductase, Apoptosis
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Related Pathways
Apoptosis, Metabolism, Endocrinology/Hormones
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CAS Number
100703
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Molecular Formula
C14H13NO3
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Molecular Weight
243.26
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SMILES
C(C)(=O)N1C(=CC(OC(C)=O)=C1)C2=CC=CC=C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound