Apremilast-d5 - CAS 1258597-47-5

Apremilast D5 (CC-10004 D5) is a deuterium-labeled Apremilast. Apremilast is an orally available inhibitor of PDE-4 (IC50: 74 nM) . Apremilast inhibits TNF-α release by lipopolysaccharide (IC50: 104 nM) .

PDE, Apoptosis, TNF

Apoptosis, Metabolism

1258597-47-5

C22H24N2O7S

465.53

[2H]C([2H])([2H])C([2H])([2H])Oc1cc(ccc1OC)[C@@H](CS(C)(=O)=O)N1C(=O)c2cccc(NC(C)=O)c2C1=O

-20°C

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