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APTO-253 - CAS 916151-99-0
APTO-253 - CAS 916151-99-0
SKU:MF-0004444-01
Regular price
$36.91 USD
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Sale price
$36.91 USD
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Product Details
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Bioactivity
APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor.
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Target
KLF, Apoptosis, c-Myc
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Related Pathways
Cell Cycle/Checkpoint, Apoptosis, MAPK
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CAS Number
916052
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Purity
0.9943
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Molecular Formula
C22H14FN5
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Molecular Weight
367.38
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SMILES
Cc1[nH]c2ccc(F)cc2c1-c1nc2c([nH]1)c1cccnc1c1ncccc21
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound