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Molfinity

APX-115 free base - CAS 1270084-92-8

APX-115 free base - CAS 1270084-92-8

MF-0004445-01

$41.39 USD
$41.39 USD
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Product Details

  • Bioactivity

    APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with inhibition constants (Kis) of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4, respectively, and it effectively prevents kidney injury.

  • Target

    NADPH-oxidase, NADPH

  • Related Pathways

    Immunology/Inflammation, Metabolism

  • CAS Number

    1269984

  • Purity

    0.9903

  • Molecular Formula

    C17H17N3O

  • Molecular Weight

    279.34

  • SMILES

    CCCc1c(O)n(nc1-c1ccccc1)-c1ccccn1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound