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Molfinity

APX2039 - CAS 2342606-49-7

APX2039 - CAS 2342606-49-7

SKU:MF-0012681-01

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  • Bioactivity

    APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity against C. neoformans and C. gattii.APX2039 exhibits potent antifungal activity and blocks the localization of GPI (glycosylphosphatidylinositol) anchored cell wall mannoproteins. APX2039 has potent antifungal activity and blocks the localization of GPI (glycosylphosphatidylinositol) -anchored cell wall mannoproteins.APX2039 can be used to study cryptococcal meningitis (CM) .

  • Target

    Antifungal

  • Related Pathways

    Microbiology/Virology

  • CAS Number

    2342550

  • Purity

    0.9907

  • Molecular Formula

    C20H15FN4O2

  • Molecular Weight

    362.36

  • SMILES

    Nc1ncccc1-c1cc(Cc2ccc(Oc3cccc(F)n3)cc2)no1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound