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AQP4 (205-215) - CAS 2891466-35-4
AQP4 (205-215) - CAS 2891466-35-4
SKU:MF-0063080-01
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Product Details
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Bioactivity
AQP4 (205-215) is a fragment of the water channel protein Aquaporin-4 (AQP4) . This protein is an autoimmune antigen in optic neuromyelitis and, upon binding with CD40, is upregulated and presented in B cells. AQP4 is associated with neuromyelitis optica (NMO), an autoimmune inflammatory disease of the central nervous system (CNS) .
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Target
Aquaporin
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Related Pathways
Membrane transporter/Ion channel
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CAS Number
2891466-35-4
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Molecular Formula
C48H75N13O17S
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Molecular Weight
1138.25
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SMILES
C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CC(N)=O)=O)=O)[C@@H](C)O)=O)=O)C)=O)CO)=O)CCSC)=O)CC(N)=O)(=O)N2[C@H](C(N[C@H](C(O)=O)C)=O)CCC2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide