AQX-016A - CAS 849669-54-1

AQX-016A is an orally active and potent SHIP1 agonist. It is a structural analog of pelorol and is three times more potent than the marine natural product pelorol at the same molar concentration. AQX-016A can activate recombinant SHIP1 enzyme in vitro and stimulate SHIP1 activity. It also inhibits the PI3K pathway and TNFa production, making it useful for various inflammatory diseases research [1] [2].

Others, PI3K, Phosphatase, TNF

PI3K/Akt/mTOR signaling, Others, Apoptosis, Metabolism

849614

C22H32O2

328.49

[H][C@]12Cc3c(c(C)cc(O)c3O)[C@]1(C)CC[C@@]1([H])C(C)(C)CCC[C@]21C

-20°C

Ice Packs

Small Compound