AQX-435 - CAS 1619983-52-6

AQX-435 is a potent activator of SHIP1 (SH2 domain-containing inositol-5′-phosphatase 1) . AQX-435 decreases B-cell receptor (BCR) downstream PI3K activity, induces apoptosis in malignant B cells, and exhibits inhibitory effects on lymphoma growth.

Others, Apoptosis, Phosphatase

Others, Metabolism, Apoptosis

1619925

C27H34N2O4

450.57

C(=O)([C@@H]1[C@]2(C)[C@@](C[C@@H](NC(=O)C=3C=CC=NC3)[C@H]1C)(C(C)(C)CCC2)[H])C4=CC(O)=CC(O)=C4

-20°C

Ice Packs

Small Compound