AR antagonist 11 - CAS 3005979-40-5

AR antagonist 11 (Compound c2) is a selective androgen receptor antagonist with an IC50 of 0.019 μM. It is also effective against the ARF877L/T878A mutant (IC50: 1.03 μM) . Additionally, AR antagonist 11 inhibits LNCaP cell proliferation and decreases PSA protein expression (IC50: 0.54 μM) . This compound is applicable in prostate cancer (PCa) research.

Serine Protease, Androgen Receptor

Endocrinology/Hormones, Proteases/Proteasome

3005934

C20H17ClN2O

336.815

ClC1=CC=C([C@H]2[C@@]3([C@](C=4C=5C(C=CC4N2)=NC=CC5)(OCC3)[H])[H])C=C1

-20°C

Ice Packs

Small Compound