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β-AR antagonist 2 - CAS 2779507-62-7
β-AR antagonist 2 - CAS 2779507-62-7
SKU:MF-0121590-01
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Product Details
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Bioactivity
Compound 43, also known as β-AR antagonist 2, is an antagonist of β-AR with an IC50 of 0.17 μM. It inhibits the growth of mouse A549 xenograft tumors and demonstrates cardioprotective efficacy against DOX-induced heart failure in C57 mice [1].
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Target
Adrenergic Receptor
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Related Pathways
GPCR/G Protein, Neuroscience
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CAS Number
2779507-62-7
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Molecular Formula
C25H28N2O3
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Molecular Weight
404.5
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SMILES
N(C1=CC=C(OCC(CNC/C=C/C2=C(OC)C=CC=C2)O)C=C1)C3=CC=CC=C3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound