AR-R 17779 hydrochloride - CAS 178419-42-6

AR-R17779 hydrochloride is a potent, selective full agonist of the nAChR, demonstrating K i values of 92 nM for the α7 subtype and 16,000 nM for the α4β2 subtype. It is noted for its ability to enhance learning and memory in rats, suggesting potential therapeutic applications. Additionally, this compound exhibits anxiolytic properties and can mitigate inflammation by activating anti-inflammatory cholinergic (vagal) pathways [1] [2] [4].

Others, AChR

Neuroscience, Others

178371

C9H15ClN2O2

218.68

Cl.O=C1NC[C@@]2(CN3CCC2CC3)O1

-20°C

Ice Packs

Small Compound