Ara-G - CAS 38819-10-2

Ara-G is a deoxyguanosine (GdR) analog and a nucleoside analogue that is rapidly converted by cells of the T lymphoid lineage to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and selective in vitro toxicity to T lymphoblastoid cell lines as well as to freshly isolated leukemia cells from patients with T cell acute lymphoblastic leukemia (ALL) .

Nucleoside Antimetabolite/Analog, Others

Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair

38807

0.9993

C10H13N5O5

283.24

Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O

-20°C

Ice Packs

Small Compound