Arachidonoyl-N, N-dimethyl amide - CAS 45280-17-9

Arachidonoyl-N, N-dimethyl amide (Arachidonic acid-N, N-dimethyl amide) is an endogenous cannabinoid that interacts with central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Its biological activity is terminated through cellular uptake and hydrolysis of the amide bond by fatty acid amide hydrolase. As an analog of arachidonoyl amide, it binds weakly or not at all to human central cannabinoid (CB1) receptors (Ki >1 μM) . At a concentration of 50 μM, it can fully inhibit gap junction intercellular communication in rat glial cells.

Cannabinoid Receptor

GPCR/G Protein

45280-17-9

C22H37NO

331.54

C(/C=C\C/C=C\C/C=C\C/C=C\CCCCC)CCC(N(C)C)=O

-20°C

Ice Packs

Natural Product