ARD-2051 - CAS 2632305-17-8

ARD-2051 is a potent, orally active proteolysis-targeting chimera degrader of the androgen receptor (AR), exhibiting DC50 values of 0.6 nM in degrading AR protein within LNCaP and VCaP prostate cancer cell lines. It holds potential for prostate cancer research applications [1].

Androgen Receptor, PROTACs

PROTAC, Endocrinology/Hormones

2632280

C43H45ClN8O5

789.32

C[C@H]1CC2(CN1C3=CC(Cl)=C(C#N)C=C3)CCN(CC2)C4=CC=C(C(=O)N5CCN(CC5)C6CN(C6)C=7C=C8C(=CC7)C(=O)N(C8=O)C9C(=O)NC(=O)CC9)C=C4

-20°C

Ice Packs

PROTAC