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Molfinity

Ardeemin - CAS 148441-25-2

Ardeemin - CAS 148441-25-2

SKU:MF-0126040-01

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  • Bioactivity

    Ardeemin ((-) -Ardeemin) binds to P-glycoprotein, inhibiting the efflux of anticancer drugs from cells. In breast cancer xenograft models, Ardeemin can reverse the multidrug resistance phenotype of tumor cells and enhance their sensitivity to anticancer drugs.

  • Target

    P-gp

  • Related Pathways

    Membrane transporter/Ion channel, Neuroscience

  • CAS Number

    148441-25-2

  • Molecular Formula

    C26H26N4O2

  • Molecular Weight

    426.51

  • SMILES

    [C@@](C=C)(C)(C)[C@]12[C@](N3[C@@](C1)(C=4N([C@H](C)C3=O)C(=O)C=5C(N4)=CC=CC5)[H])(NC=6C2=CC=CC6)[H]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product