Aristolactam I - CAS 13395-02-3

1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF-beta1 pathway. 3. Aristololactam I may be one of toxic metabolites in Chinese herbs containing AA which participate in renal damage and fibrosis.

Drug Metabolite, Cadherin, Aquaporin, Caspase, Apoptosis, TGF-beta/Smad

Membrane transporter/Ion channel, Stem Cells, Apoptosis, Cytoskeletal Signaling, Metabolism, Proteases/Proteasome

13395-02-3

0.9963

C17H11NO4

293.27

COc1cccc2c1cc1NC(=O)c3cc4OCOc4c2c13

-20°C

Ice Packs

Natural Product