Aristolochic acid A - CAS 313-67-7

Aristolochic acid A is the main component of the plant extract aristolochic acids, primarily found in the herbaceous plants Aristolochia and Asarum. It significantly inhibits the activity of activator protein 1 (AP-1) and NF-κB, and downregulates the expression of the bladder cancer-associated BLCAP gene in human cells. It is commonly used to induce nephrotoxicity models.

NF-κB

NF-κB

239

0.9997

C17H11NO7

341.27

COc1cccc2c1cc([N+]([O-])=O)c1c(cc3OCOc3c21)C(O)=O

-20°C

Ice Packs

Natural Product