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ARN-6039 - CAS 1675206-11-7
ARN-6039 - CAS 1675206-11-7
SKU:MF-0063190-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
ARN-6039, an orally available inverse agonist of RORγ, targets Autoimmune Neuroinflammatory Demyelinating Disease. Its efficacy was demonstrated in a RORγ-activated IL-17A Prom/LUCPorter assay in HEK 293 cells (360 nM) and in IL-17 release from CD4+T cell assays (220 nM) .
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Target
Others, ROR
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Related Pathways
Metabolism, Others
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CAS Number
1675188
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Molecular Formula
C21H21F3N2O3
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Molecular Weight
406.4
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SMILES
COc1cc2C(=O)C(Cc3ncccc3C(F)(F)F)Cc2cc1N1CCOCC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound